Local cutaneous allergy to monocomponent insulin.

Primary allergy to monocomponent porcine insulin.

An allergic reaction, occurring in a patient who has been put on monocomponent insulin for the first time, is extremely rare. A case of primary allergy to monocomponent porcine insulin, and its subsequent management, is described here.

Spontaneous pseudomembranous colitis.

Goldstein HH. Allergy and diabetes. In: Joslin's diabetes mellitus. 11th edn. Philadelphia: Lea and Febiger, 1971. 2 Leslie D. Generalised allergic reaction to monocomponent insulin. Br MedJ 1977;ii :736-7. 3 Sewell H, Smith DI, Willox A, Barnes CA, Matthews JB. Demonstration of islet cell antibodies. Lancet 1980;i :102-3. 4 Davidson JA, Galloway JA, Peterson BH, et al. The use of purified insu...

Vaccination scar with soft-tissue atrophy restored by local insulin treatment.

A woman who had a deep scar on her left arm as a result of an influenza vaccination was treated with insulin. Monocomponent porcine insulin was injected into each quadrant of the pit. After 82 days' treatment her arm appeared normal and has remained so over seven months. Using insulin's ability to promote fat and protein synthesis is a simple and effective way of treating atrophied scars.

Precipitin reaction between bovine insulin, porcine insulin, monocomponent insulin and guinea pig antibovine insulin sera.

Animal Insulins - Current Status

There is no significant difference in the metabolic control with animal or human insulin. At present there is no clinical data comparing the diabetes related mortality and complications, with animal or human insulin. The earlier animal insulins were more immunogenic as compared to human insulin, but the present day highly purified monocomponent insulins are less antigenic and the difference in ...